Pericarditis: Causes, Symptoms, Treatment & Recovery for Nursing Students
- Grace

- 11 hours ago
- 6 min read

What Is Pericarditis?
Pericarditis is the inflammation of the pericardium, the thin two-layered sac surrounding the heart. Between these layers lies a small amount of lubricating fluid that allows the heart to beat without friction. When this sac becomes inflamed, fluid can accumulate, causing sharp chest pain, breathing difficulty, and—if untreated—potential complications such as pericardial effusion or cardiac tamponade.
In emergency settings, pericarditis accounts for up to 5% of chest-pain cases unrelated to heart attack. For nursing students, learning to differentiate pericarditis from myocardial infarction is essential.
Understanding the inflammation of the heart’s protective sac — and why recognizing it early saves lives.
Who Gets Pericarditis — and Why?
Who?
Anyone can develop pericarditis, but it is most common in:
Adults aged 20–50
Men, who statistically show higher rates in viral and vaccine-associated cases
Pericarditis (inflammation of the lining around the heart) and myocarditis (inflammation of the heart muscle) are rare, but recognized, adverse events associated with mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna), particularly in adolescent and young adult males, usually within several days after the second dose.
Individuals recovering from infections
Patients with autoimmune or chronic inflammatory diseases
Where & When?
In North America, most cases are viral or idiopathic (cause unknown but presumed viral).
In developing nations, tuberculosis remains a major cause.
Symptoms often begin suddenly, typically following an infection or immune system trigger.

What Causes Pericarditis?
1. Viral Infections (Most Common Cause)
Viruses linked with pericarditis include:
These infections trigger inflammation in the pericardial sac, causing sharp pain and potential fluid buildup.
2. Autoimmune & Systemic Inflammatory Disorders
Conditions that may involve the pericardium include:
In these cases, the immune system mistakenly attacks the pericardium.
3. Post-Cardiac Injury
Pericarditis can occur after:
Heart surgery
Chest trauma
Heart attack (Dressler Syndrome)
Certain medical procedures (catheter-based)
4. Environmental Influences
Environmental contributors may include:
Chest radiation therapy
Exposure to toxins or chemicals
Severe physical stress
5. Genetic Susceptibility
While no single “pericarditis gene” exists, people with:
Autoinflammatory conditions (e.g., IL-1 pathway disorders)
Strong family history of autoimmune disease
Abnormal inflammatory responses
…are more likely to experience recurrent or persistent pericarditis.
6. Vaccine-Associated Pericarditis (Rare but Documented)
Modern studies show that mRNA COVID-19 vaccines are associated with a very small increase in pericarditis and myocarditis, especially in:
Younger males
After the second dose
Within 7–14 days of vaccination
Key points for balanced reporting:
Cases are rare.
Symptoms usually resolve with treatment.
COVID-19 infection itself carries a significantly higher risk of heart inflammation.
SGMA maintains a neutral, evidence-based view: acknowledge the data without bias, fear, or propaganda.
Resources:

How Does Pericarditis Present? (Signs & Symptoms)
Classic Symptoms
Patients often describe:
Sharp, stabbing chest pain that worsens when lying flat
Pain that improves when sitting up and leaning forward
Pain radiating to the neck, shoulders, or left trapezius
Shortness of breath
Low-grade fever
Fatigue and malaise
Physical Examination Findings
Pericardial friction rub (a scratchy sound heard on auscultation)
Distant/muffled heart sounds (with large effusions)
ECG Changes
No reciprocal ST depressions (helps differentiate from MI)
Potential Complications
Cardiac tamponade (life-threatening)
Constrictive pericarditis (scarred, stiff pericardium)
Diagnosis: How Healthcare Providers Confirm It
Key diagnostic tools:
ECG
Echocardiogram (checks for effusion)
Chest X-ray
Cardiac MRI (for recurrent or complex cases)
Blood tests
CRP, ESR
CRP stands for C-reactive protein, a substance made by the liver in response to inflammation in the body, and a CRP test measures its levels in your blood. High CRP levels indicate inflammation caused by infections, injuries, or chronic diseases like arthritis, but the test alone cannot identify the location or cause. Further tests are often needed to pinpoint the underlying issue.
Troponin (to rule out myocarditis/MI)
Thyroid function, kidney function
Autoimmune screening when indicated

Treatment Options
Western Medicine (Primary Evidence-Based Approach)
1. First-Line Treatment
✔ NSAIDs (Ibuprofen, high-dose Aspirin)
✔ Colchicine (3 months for first episode; up to 12 months for recurrences)
✔ Rest
✔ Gradual return to activity once pain and CRP improve
2. Second-Line Treatment
Used in chronic, recurrent, or refractory cases:
Corticosteroids (low dose, limited duration)
IL-1 inhibitors (Anakinra or Rilonacept)
Immunosuppressants (in severe autoimmune disease)
3. Procedures (If Required)
Pericardiocentesis for large effusions or tamponade
Pericardiectomy for constrictive pericarditis
Traditional, Complementary & Home Support
1. Lifestyle Approaches
Adequate rest during acute phase
Avoiding heavy lifting for 2–4 weeks
Anti-inflammatory diet:
Omega-3 rich foods (salmon, flaxseed, walnuts)
Turmeric, ginger, berries
Minimizing processed foods
Maintaining hydration
Stress-reduction practices (meditation, breathwork, light yoga)
2. Herbal Supports
(Adjuncts only, not replacements)
Turmeric (curcumin)
Ginger tea
Hawthorn (caution with cardiac medications)
Boswellia
Always encourage patients to discuss supplements with a healthcare provider to prevent interactions.
3. Men’s Mental & Physical Health Considerations
Men often:
Delay reporting chest pain
Hide symptoms from family
Associate vulnerability with weakness
Include emotional check-ins:
“How is this affecting your stress?”
“Are you feeling worried, frustrated, or scared?”
“Is your sleep disrupted?”
Addressing mental health improves recovery outcomes.
Home Treatment & Self-Care
Acute Phase
Rest and minimize physical activity
Use NSAIDs as prescribed
Stay upright or sleep with the head elevated to reduce pain
Hydrate consistently
Track symptoms (pain score, breathing difficulty)
Recovery Phase
Slowly reintroduce light activity
Add heart-healthy foods
Incorporate stress-reduction practices
Avoid alcohol until inflammation fully resolves
Attend all follow-up appointments
Report new chest pain immediately
When to Seek Emergency Help
Sudden worsening shortness of breath
Feeling faint or light-headed
Rapid heartbeat
Chest pressure not relieved by rest
Swelling in legs or abdomen
Long-Term Outlook
Most patients with viral or idiopathic pericarditis recover fully. However:
15–30% experience recurrence
Early treatment reduces recurrence risk
Following the NSAID + colchicine protocol is essential
Avoid rushing back into strenuous activity
Long-term care includes:
Monitoring inflammatory markers
Follow-up echocardiograms
Managing stress for overall heart–mind balance

Case Scenario for Nursing Students
(With rationale)
A 29-year-old male presents with sharp chest pain 10 days after recovering from influenza. Pain worsens while lying down and improves when he leans forward. ECG shows diffuse ST elevation. CRP elevated.
Questions
What is your likely diagnosis?
Rationale: Sharp pleuritic chest pain + positional symptoms + diffuse ST elevations strongly suggest acute pericarditis.
What immediate management is recommended?
Rationale: NSAIDs + colchicine are first-line. Rest is essential. Evaluate for effusion with an echocardiogram.
What complications should you watch for?
Rationale: Cardiac tamponade (look for hypotension, JVD, muffled heart sounds) and pericardial effusion.
How is this different from a myocardial infarction?
Rationale: MI has localized ST elevation with reciprocal depression; pericarditis has diffuse changes.
This scenario reinforces critical thinking and symptom interpretation for nursing students.
Conclusion
Pericarditis is a complex but often manageable condition when recognized early. With proper care, lifestyle adjustments, and follow-up, most individuals make a full recovery. As we continue focusing on men’s mental and physical health, reminding patients—especially men—that chest pain should never be ignored is a powerful step toward prevention and early treatment.
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Author - Saving Grace Medical Academy Ltd
Grace. T
Medical Content Writer






